• June 19, 2021
hematoonkologia

Interleukina-23 zamiast interleukiny-12 jest

Interleukina-23 zamiast interleukiny-12 jest cytokiną krytyczną dla autoimmunologicznego zapalenia mózgu.  Interleukin-12 (IL-12) is a heterodimeric molecule composed of p35 and p40 subunits. Analyses in vitro have outlined IL-12 as an essential issue for the differentiation of naive T cells into T-helper sort 1 CD4+ lymphocytes secreting interferon-gamma (refs 1, 2). Equally, quite a few research have concluded that IL-12…

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hematoonkologia

Synapsa immunologiczna: molekularna maszyna

Synapsa immunologiczna: molekularna maszyna kontrolująca aktywację limfocytów T.  The specialised junction between a T lymphocyte and an antigen-presenting cell, the immunological synapse, consists of a central cluster of T cell receptors surrounded by a hoop of adhesion molecules. Immunological synapse formation is now proven to be an lively and dynamic mechanism that permits T cells to differentiate potential antigenic ligands. Initially, T cell receptor…

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