• 30 kwietnia, 2021
hematoonkologia

Sierocy receptor jądrowy RORgammat

Sierocy receptor jądrowy RORgammat kieruje programem różnicowania prozapalnych komórek pomocniczych IL-17 + T. 

IL-17-producing T lymphocytes have been lately proven to comprise a definite lineage of proinflammatory T helper cells, termed Th17 cells, which can be main contributors to autoimmune illness. We present right here that the orphan nuclear receptor RORgammat is the important thing transcription issue that orchestrates the differentiation of this effector cell lineage. RORgammat induces transcription of the genes encoding IL-17 and the associated cytokine IL-17F in naïve CD4(+) T helper cells and is required for his or her expression in response to IL-6 and TGF-beta, the cytokines identified to induce IL-17.

Th17 cells are constitutively current all through the intestinal lamina propria, categorical RORgammat, and are absent in mice poor for RORgammat or IL-6. Mice with RORgammat-deficient T cells have attenuated autoimmune illness and lack tissue-infiltrating Th17 cells. Collectively, these research counsel that RORgammat is a key regulator of immune homeostasis and spotlight its potential as a therapeutic goal in inflammatory ailments.

hematoonkologia
hematoonkologia

Ccl2 CRISPR Knock Out CT26 Cell Line

T9611 1x10^6 cells / 1.0 ml Ask for price

CXCL8 CRISPR Knock Out L3.6pl Cell Line

T6220 1x10^6 cells / 1.0 ml Ask for price

CXCL1 CRISPR Knock Out L3.6pl Cell Line

T6221 1x10^6 cells / 1.0 ml Ask for price

FOLR CRISPR Knock Out Human OVCAR3-A1 Cell Line

T6229 1x10^6 cells / 1.0 ml Ask for price

MUC16 CRISPR Knock Out Human OVCAR3-A1 Cell Line

T6230 1x10^6 cells / 1.0 ml Ask for price

NR2F6 CRISPR Knock Out Human Jurkat E6.1 Cell Line - Clone T3-10

T6822 1x10^6 cells / 1.0 ml Ask for price

TREM2 CRISPR Knock Out Human THP-1 Cell Line - Clone T1-9

T6810 1x10^6 cells / 1.0 ml Ask for price

PTPN6 CRISPR Knock Out Human THP-1 Cell Line - Clone T3-1

T6813 1x10^6 cells / 1.0 ml Ask for price

Aldh2 CRISPR Knock Out L929 Cell Line - Clone T3-20

T9692 1x10^6 cells / 1.0 ml Ask for price

PTPN11 CRISPR Knock Out NIH/3T3 Cell Line - Clone T4-9

T6803 1x10^6 cells / 1.0 ml Ask for price

METTL3 CRISPR Knock Out Caki-1 Cell Line - Clone T2-16

T9623 1x10^6 cells / 1.0 ml
EUR 3950

Nacc1 CRISPR Knock Out ID8 Cell Line (Mouse) - Clone T1-23

T9627 1x10^6 cells / 1.0 ml Ask for price

osbpl2 CRISPR Knock Out NIH/3T3 Cell Line - T1 Polyclonal Pool

T9682 1x10^6 cells / 1.0 ml Ask for price

GLT1 CRISPR Knock Out Rat AST Cell Line - Clone T2-1

T9678 1x10^6 cells / 1.0 ml Ask for price

PRSS21 CRISPR Knock Out Human OVCAR8 Cell Line - Clone T2 C8

T6811 1x10^6 cells / 1.0 ml Ask for price

Aifm1 CRISPR Knock Out Mouse L929 Cell Line - Clone T2-15-3

T9674 1x10^6 cells / 1.0 ml Ask for price

SEC61G CRISPR Knock Out HCC-LM3 Cell Line - Clone T2-17-5

T9746 1x10^6 cells / 1.0 ml Ask for price

MSLN CRISPR Knock Out Human OVCAR3-A1 Cell Line - Clone T2 C4

T6820 1x10^6 cells / 1.0 ml Ask for price

CARMIL1 CRISPR Knock Out Immortalized Human Gingival Fibroblast - hTERT Cell Line - T1-2

T6825 1x10^6 cells / 1.0 ml Ask for price

hPIM1 CRISPR Knock Out SACC-83 Cell Line-T3-9

T9787 1x10^6 cells / 1.0 ml Ask for price

Dcx CRISPR Knock Out C6 Cell Line (Rat) - Clone sg4-1

T9624 1x10^6 cells / 1.0 ml
EUR 3950

Cell line gene knock-in and knock-out

S301 -
EUR 15000

Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T1-19

T9511 1x10^6 cells / 1.0 ml
EUR 3950

SIRT1 Knockout Stable 293T Cell Line

T3176 1x10^6 cells / 1.0 ml
EUR 3950

Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T3-3

T9529 1x10^6 cells/1.0ml
EUR 3950

T47D/GFP Cell Line

AKR-208 1 vial
EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

Human LCK knockout cell line

ABC-KH8337 1 vial Ask for price
Description: Human LCK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LCK knockdown cell line

ABC-KD8337 1 vial Ask for price
Description: Human LCK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Stable Mouse Myeloid-derived Suppressor-like LAL Knock Out (HD1B) Cell Line

T3187 1x10^6 cells / 1.0 ml
EUR 3950

293T Cell Line

LV010 1x10^6
EUR 450

293T [HEK-293T] Cell Line

CL-0005 1×10⁶ cells/vial
EUR 420
Description: Homo sapiens, Human

293T/17 Cell Line

CL-0469 1×10⁶ cells/vial
EUR 500
Description: Homo sapiens, Human

293T Cell Lysate (Human embryonic kidney cell line)

LF-R0006 200 ul
EUR 103.2
Description: 293T (Human embryonic kidney cell line) Whole Cell Lysate

293AD Cell Line

AD-100 1 vial
EUR 365

293AAV Cell Line

AAV-100 1 vial
EUR 405

293LTV Cell Line

LTV-100 1 vial
EUR 405

293RTV Cell Line

RV-100 1 vial
EUR 405

293/GFP Cell Line

AKR-200 1 vial
EUR 460

A549/GFP Cell Line

AKR-209 1 vial
EUR 460

HeLa/GFP Cell Line

AKR-213 1 vial
EUR 460

293/Cas9 Cell Line

AKR-5110 1 vial
EUR 460

HeLa/Cas9 Cell Line

AKR-5111 1 vial
EUR 460

NIH3T3/GFP Cell Line

AKR-214 1 vial
EUR 460

NIH3T3/Cas9 Cell Line

AKR-5104 1 vial
EUR 460

Cas9 Expressing 293T Cell Line

T3251 1x10^6 cells / 1.0 ml
EUR 795

MCF-7/Luc Cell Line

AKR-234 1 vial
EUR 686.4
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

SKOV-3/Luc Cell Line

AKR-232 1 vial
EUR 686.4
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

OVCAR-5/RFP Cell Line

AKR-254 1 vial
EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.

Blank Promoter Stable Expressing Human 293T Cell Line

T9618 1x10^6 cells / 1.0 ml
EUR 3950

Stable 293T-ATD cell line

T6340 1x10^6 cells / 1.0 ml
EUR 3950

Mouse NACC1 CRISPR Stable Knockout ID8 Cell Line - Clone T1-23

T6826 1x10^6 cells / 1.0 ml
EUR 3950

PTPN6 Stable Knocked Out THP-1 Cell Line

T6216 1x10^6 cells / 1.0 ml
EUR 3950

SIRT1 Wildtype Stable 293T Cell Line

T3175 1x10^6 cells / 1.0 ml
EUR 3950

Platinum-E Retroviral Packaging Cell Line, Ecotropic

RV-101 1 vial
EUR 770

Platinum-GP Retroviral Packaging Cell Line, Pantropic

RV-103 1 vial
EUR 770

Platinum-A Retroviral Packaging Cell Line, Amphotropic

RV-102 1 vial
EUR 770

Total Protein - Murine Embryonic Stem Cell Line D3

CBA-305 500 ?g
EUR 414
Description:
  • Isolated from mouse ES-D3 cell line
  • Presented as 500 µg at 1 mg/mL in NP-40 Solubilization Buffer

PGC-1α/ERRα Stable 293T Cell Line

T3060 1x10^6 cells / 1.0 ml
EUR 385

Mouse R-spondin1 Stable 293T Cell Line

T3156 1x10^6 cells / 1.0 ml
EUR 3950

BRCA1 CRISPR Stable Knockout Human Fibroblast Cell Line

T6245 1x10^6 cells / 1.0 ml
EUR 3950

PFN2 Stable Expressing 293T Cell Line - Polyclonal

T9606 1x10^6 cells / 1.0 ml
EUR 3950

PLN Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS41 1 Vial
EUR 2268

LRP1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS31 1 Vial
EUR 2268

AFF2 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS61 1 Vial
EUR 2268

ABCA7 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS21 1 Vial
EUR 2268

KCNK3 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS51 1 Vial
EUR 2268

LLGL1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS71 1 Vial
EUR 2268

TARGATT? Knock-in Mouse Cell Line Generation Kit (Master Cell Line)

AST-7001 1 Kit Ask for price
Description: 6 month

Human CRISP1 knockout cell line

ABC-KH3569 1 vial Ask for price
Description: Human CRISP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISP2 knockout cell line

ABC-KH3570 1 vial Ask for price
Description: Human CRISP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISP3 knockout cell line

ABC-KH3571 1 vial Ask for price
Description: Human CRISP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

PTPRA CRISPR Knockout Immortalized Human Lung Fibroblast Cell Line

T6827 1x10^6 cells / 1.0 ml Ask for price

YBX1 Stable Knockout Human NK/T Cell Line #T3-16 P6

T9508 1x10^6 cells / 1.0 ml Ask for price

Human CRISPLD1 knockout cell line

ABC-KH3572 1 vial Ask for price
Description: Human CRISPLD1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISPLD2 knockout cell line

ABC-KH3573 1 vial Ask for price
Description: Human CRISPLD2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

TARGATT? Knock-in iPSC Generation (Master Cell Line)

AST-1100 1 vial of 1X10^6 cells Ask for price
Description: 6 month

Human 293T Cell Lysate Lyophilized

IHU293TTLLY200UG each
EUR 89
Description: Human 293T Cell Lysate Lyophilized

Acan CRISPR Knockout RCS Cell Line (Rat)

T3000 1x10^6 cells / 1.0 ml Ask for price

Human CRISP1 knockdown cell line

ABC-KD3569 1 vial Ask for price
Description: Human CRISP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISP2 knockdown cell line

ABC-KD3570 1 vial Ask for price
Description: Human CRISP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISP3 knockdown cell line

ABC-KD3571 1 vial Ask for price
Description: Human CRISP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human 293T Whole Cell Lysate

LYSATE0032 200ug
EUR 180
Description: This cell lysate is prepared from human 293T using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Human CRISPLD1 knockdown cell line

ABC-KD3572 1 vial Ask for price
Description: Human CRISPLD1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISPLD2 knockdown cell line

ABC-KD3573 1 vial Ask for price
Description: Human CRISPLD2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

TARGATT? Knock-in CHO Generation Kit (Master Cell Line)

AST-1200 1 Kit Ask for price
Description: 12 month

VEGF Promoter Stable Expressing 293T Cell Line - Clone #2

T9622 1x10^6 cells / 1.0 ml
EUR 3950

AAVS1 Positive Control EGIP 293T Reporter Cell Line

CAS606A-1 1 Vial
EUR 726

TARGATT? Knock-in HEK293 Generation Kit (Master Cell Line)

AST-1300 1 Kit Ask for price
Description: 12 month

GFAT1 CRISPR Stable Knockout H1299 Cell Line

T6199 1x10^6 cells / 1.0 ml
EUR 3950

EDC4 CRISPR Stable Knockout HEK293T Cell Line

T6241 1x10^6 cells / 1.0 ml
EUR 3950

293T Cell Lysates

GWB-E5C7FC 0.2 mg Ask for price

DJ-1 CRISPR Stable Knockout HeLa Cell Line

T6181 1x10^6 cells / 1.0 ml
EUR 3950

PDPN CRISPR Stable Knockout COS-7 Cell Line

T6039 1x10^6 cells / 1.0 ml
EUR 3950

PD-L1 CRISPR Stable Knockout CT26 Cell Line

T6237 1x10^6 cells / 1.0 ml
EUR 3950

PD-L1 CRISPR Stable Knockout MC38 Cell Line

T6149 1x10^6 cells / 1.0 ml
EUR 3950

LIMD1-/- CRISPR Stable Knockout HeLa Cell Line

T6357 1x10^6 cells / 1.0 ml
EUR 3950

SLC35A1 CRISPR Stable Knockout CHO-S Cell Line

T6040 1x10^6 cells / 1.0 ml
EUR 3950

CXCL1 & CXCL8 CRISPR Double Knockout L3.6pl Cell Line

T6047 1x10^6 cells / 1.0 ml Ask for price

AXL CRISPR Stable Knockout HT1080 (1-IV) Cell Line

T6232 1x10^6 cells / 1.0 ml
EUR 3950

AXL CRISPR Stable Knockout HT1080 (3-II) Cell Line

T6233 1x10^6 cells / 1.0 ml
EUR 3950

hCETP shRNA (Target C) Knock Down THP-1 Cell Line-Polyclone

T9789 1x10^6 cells / 1.0 ml Ask for price

Human CRIM1 knockout cell line

ABC-KH3563 1 vial Ask for price
Description: Human CRIM1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP1 knockout cell line

ABC-KH3564 1 vial Ask for price
Description: Human CRIP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP2 knockout cell line

ABC-KH3565 1 vial Ask for price
Description: Human CRIP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP3 knockout cell line

ABC-KH3566 1 vial Ask for price
Description: Human CRIP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIPT knockout cell line

ABC-KH3568 1 vial Ask for price
Description: Human CRIPT knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIPAK knockout cell line

ABC-KH3567 1 vial Ask for price
Description: Human CRIPAK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Cas9 (CRISPR Associated Protein 9) ELISA Kit

PRB-5079 96 assays
EUR 485

Human CRIM1 knockdown cell line

ABC-KD3563 1 vial Ask for price
Description: Human CRIM1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP1 knockdown cell line

ABC-KD3564 1 vial Ask for price
Description: Human CRIP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP2 knockdown cell line

ABC-KD3565 1 vial Ask for price
Description: Human CRIP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP3 knockdown cell line

ABC-KD3566 1 vial Ask for price
Description: Human CRIP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIPT knockdown cell line

ABC-KD3568 1 vial Ask for price
Description: Human CRIPT knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIPAK knockdown cell line

ABC-KD3567 1 vial Ask for price
Description: Human CRIPAK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human LIN37 knockout cell line

ABC-KH8476 1 vial Ask for price
Description: Human LIN37 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GC knockout cell line

ABC-KH5948 1 vial Ask for price
Description: Human GC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GK knockout cell line

ABC-KH6087 1 vial Ask for price
Description: Human GK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human HP knockout cell line

ABC-KH6972 1 vial Ask for price
Description: Human HP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human HR knockout cell line

ABC-KH6992 1 vial Ask for price
Description: Human HR knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human KL knockout cell line

ABC-KH7942 1 vial Ask for price
Description: Human KL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika sprzyja przywilejowi immunologicznemu i pozwala przewidzieć skrócenie czasu przeżycia. 

Regulatory T (T(reg)) cells mediate homeostatic peripheral tolerance by suppressing autoreactive T cells. Failure of host antitumor immunity could also be attributable to exaggerated suppression of tumor-associated antigen-reactive lymphocytes mediated by T(reg) cells; nevertheless, definitive proof that T(reg) cells have an immunopathological function in human most cancers is missing. Right here we present, in detailed research of CD4(+)CD25(+)FOXP3(+) T(reg) cells in 104 people affected with ovarian carcinoma, that human tumor T(reg) cells suppress tumor-specific T cell immunity and contribute to progress of human tumors in vivo.

We additionally present that tumor T(reg) cells are related to a excessive demise hazard and decreased survival. Human T(reg) cells preferentially transfer to and accumulate in tumors and ascites, however not often enter draining lymph nodes in later most cancers phases. Tumor cells and microenvironmental macrophages produce the chemokine CCL22, which mediates trafficking of T(reg) cells to the tumor. This particular recruitment of T(reg) cells represents a mechanism by which tumors might foster immune privilege. Thus, blocking T(reg) cell migration or perform might assist to defeat human most cancers.

Płynny mannequin mozaiki struktury błon komórkowych. 

A fluid mosaic mannequin is offered for the gross group and construction of the proteins and lipids of organic membranes. The mannequin is according to the restrictions imposed by thermodynamics. On this mannequin, the proteins which can be integral to the membrane are a heterogeneous set of globular molecules, every organized in an amphipathic construction, that’s, with the ionic and extremely polar teams protruding from the membrane into the aqueous part, and the nonpolar teams largely buried within the hydrophobic inside of the membrane. These globular molecules are partially embedded in a matrix of phospholipid. The majority of the phospholipid is organized as a discontinuous, fluid bilayer, though a small fraction of the lipid might work together particularly with the membrane proteins.

The fluid mosaic construction is due to this fact formally analogous to a two-dimensional oriented resolution of integral proteins (or lipoproteins) within the viscous phospholipid bilayer solvent. Current experiments with all kinds of techniqes and several other totally different membrane methods are described, all of which abet according to, and add a lot element to, the fluid mosaic mannequin. It due to this fact appears acceptable to counsel potential mechanisms for varied membrane capabilities and membrane-mediated phenomena within the mild of the mannequin. As examples, experimentally testable mechanisms are prompt for cell floor adjustments in malignant transformation, and for cooperative results exhibited within the interactions of membranes with some particular ligands.

Notice added in proof: Since this text was written, we’ve obtained electron microscopic proof (69) that the concanavalin A binding websites on the membranes of SV40 virus-transformed mouse fibroblasts (3T3 cells) are extra clustered than the websites on the membranes of regular cells, as predicted by the speculation represented in Fig. 7B. T-here has additionally appeared a examine by Taylor et al. (70) displaying the exceptional results produced on lymphocytes by the addition of antibodies directed to their floor immunoglobulin molecules.

The antibodies induce a redistribution and pinocytosis of those floor immunoglobulins, in order that inside about 30 minutes at 37 levels C the floor immunoglobulins are utterly swept out of the membrane. These results don’t happen, nevertheless, if the bivalent antibodies are changed by their univalent Fab fragments or if the antibody experiments are carried out at zero levels C as an alternative of 37 levels C. These and associated outcomes strongly point out that the bivalent antibodies produce an aggregation of the floor immunoglobulin molecules within the airplane of the membrane, which may happen provided that the immunoglobulin molecules are free to diffuse within the membrane. This aggregation then seems to set off the pinocytosis of the membrane parts by some unknown mechanism. Such membrane transformations could also be of essential significance within the induction of an antibody response to an antigen, in addition to iv different processes of cell differentiation.

Przywracanie funkcji wyczerpanych limfocytów T CD8 podczas przewlekłej infekcji wirusowej. 

Practical impairment of antigen-specific T cells is a defining attribute of many power infections, however the underlying mechanisms of T-cell dysfunction usually are not properly understood. To deal with this query, we analysed genes expressed in functionally impaired virus-specific CD8 T cells current in mice chronically contaminated with lymphocytic choriomeningitis virus (LCMV), and in contrast these with the gene profile of purposeful reminiscence CD8 T cells. Right here we report that PD-1 (programmed demise 1; often known as Pdcd1) was selectively upregulated by the exhausted T cells, and that in vivo administration of antibodies that blocked the interplay of this inhibitory receptor with its ligand, PD-L1 (often known as B7-H1), enhanced T-cell responses.

Notably, we discovered that even in persistently contaminated mice that had been missing CD4 T-cell assist, blockade of the PD-1/PD-L1 inhibitory pathway had a useful impact on the ‘helpless’ CD8 T cells, restoring their capacity to endure proliferation, secrete cytokines, kill contaminated cells and reduce viral load. Blockade of the CTLA-4 (cytotoxic T-lymphocyte-associated protein 4) inhibitory pathway had no impact on both T-cell perform or viral management. These research establish a particular mechanism of T-cell exhaustion and outline a probably efficient immunological technique for the remedy of power viral infections.

CXCL1 CRISPR Knock Out L3.6pl Cell Line

T6221 1x10^6 cells / 1.0 ml Ask for price

FOLR CRISPR Knock Out Human OVCAR3-A1 Cell Line

T6229 1x10^6 cells / 1.0 ml Ask for price

MUC16 CRISPR Knock Out Human OVCAR3-A1 Cell Line

T6230 1x10^6 cells / 1.0 ml Ask for price

NR2F6 CRISPR Knock Out Human Jurkat E6.1 Cell Line - Clone T3-10

T6822 1x10^6 cells / 1.0 ml Ask for price

TREM2 CRISPR Knock Out Human THP-1 Cell Line - Clone T1-9

T6810 1x10^6 cells / 1.0 ml Ask for price

PTPN6 CRISPR Knock Out Human THP-1 Cell Line - Clone T3-1

T6813 1x10^6 cells / 1.0 ml Ask for price

Aldh2 CRISPR Knock Out L929 Cell Line - Clone T3-20

T9692 1x10^6 cells / 1.0 ml Ask for price

PTPN11 CRISPR Knock Out NIH/3T3 Cell Line - Clone T4-9

T6803 1x10^6 cells / 1.0 ml Ask for price

METTL3 CRISPR Knock Out Caki-1 Cell Line - Clone T2-16

T9623 1x10^6 cells / 1.0 ml
EUR 3950

Nacc1 CRISPR Knock Out ID8 Cell Line (Mouse) - Clone T1-23

T9627 1x10^6 cells / 1.0 ml Ask for price

osbpl2 CRISPR Knock Out NIH/3T3 Cell Line - T1 Polyclonal Pool

T9682 1x10^6 cells / 1.0 ml Ask for price

GLT1 CRISPR Knock Out Rat AST Cell Line - Clone T2-1

T9678 1x10^6 cells / 1.0 ml Ask for price

PRSS21 CRISPR Knock Out Human OVCAR8 Cell Line - Clone T2 C8

T6811 1x10^6 cells / 1.0 ml Ask for price

Aifm1 CRISPR Knock Out Mouse L929 Cell Line - Clone T2-15-3

T9674 1x10^6 cells / 1.0 ml Ask for price

SEC61G CRISPR Knock Out HCC-LM3 Cell Line - Clone T2-17-5

T9746 1x10^6 cells / 1.0 ml Ask for price

MSLN CRISPR Knock Out Human OVCAR3-A1 Cell Line - Clone T2 C4

T6820 1x10^6 cells / 1.0 ml Ask for price

CARMIL1 CRISPR Knock Out Immortalized Human Gingival Fibroblast - hTERT Cell Line - T1-2

T6825 1x10^6 cells / 1.0 ml Ask for price

hPIM1 CRISPR Knock Out SACC-83 Cell Line-T3-9

T9787 1x10^6 cells / 1.0 ml Ask for price

Dcx CRISPR Knock Out C6 Cell Line (Rat) - Clone sg4-1

T9624 1x10^6 cells / 1.0 ml
EUR 3950

Human GZMA knockout cell line

ABC-KH6566 1 vial Ask for price
Description: Human GZMA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Cell line gene knock-in and knock-out

S301 -
EUR 15000

Human GZMA knockdown cell line

ABC-KD6566 1 vial Ask for price
Description: Human GZMA knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T1-19

T9511 1x10^6 cells / 1.0 ml
EUR 3950

SIRT1 Knockout Stable 293T Cell Line

T3176 1x10^6 cells / 1.0 ml
EUR 3950

Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T3-3

T9529 1x10^6 cells/1.0ml
EUR 3950

T47D/GFP Cell Line

AKR-208 1 vial
EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

Stable Mouse Myeloid-derived Suppressor-like LAL Knock Out (HD1B) Cell Line

T3187 1x10^6 cells / 1.0 ml
EUR 3950

293T Cell Line

LV010 1x10^6
EUR 450

293T [HEK-293T] Cell Line

CL-0005 1×10⁶ cells/vial
EUR 420
Description: Homo sapiens, Human

293T/17 Cell Line

CL-0469 1×10⁶ cells/vial
EUR 500
Description: Homo sapiens, Human

293T Cell Lysate (Human embryonic kidney cell line)

LF-R0006 200 ul
EUR 103.2
Description: 293T (Human embryonic kidney cell line) Whole Cell Lysate

293AD Cell Line

AD-100 1 vial
EUR 365

293AAV Cell Line

AAV-100 1 vial
EUR 405

293LTV Cell Line

LTV-100 1 vial
EUR 405

293RTV Cell Line

RV-100 1 vial
EUR 405

293/GFP Cell Line

AKR-200 1 vial
EUR 460

A549/GFP Cell Line

AKR-209 1 vial
EUR 460

HeLa/GFP Cell Line

AKR-213 1 vial
EUR 460

293/Cas9 Cell Line

AKR-5110 1 vial
EUR 460

HeLa/Cas9 Cell Line

AKR-5111 1 vial
EUR 460

NIH3T3/GFP Cell Line

AKR-214 1 vial
EUR 460

NIH3T3/Cas9 Cell Line

AKR-5104 1 vial
EUR 460

Cas9 Expressing 293T Cell Line

T3251 1x10^6 cells / 1.0 ml
EUR 795

MCF-7/Luc Cell Line

AKR-234 1 vial
EUR 686.4
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

SKOV-3/Luc Cell Line

AKR-232 1 vial
EUR 686.4
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

OVCAR-5/RFP Cell Line

AKR-254 1 vial
EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.

Blank Promoter Stable Expressing Human 293T Cell Line

T9618 1x10^6 cells / 1.0 ml
EUR 3950

Stable 293T-ATD cell line

T6340 1x10^6 cells / 1.0 ml
EUR 3950

Mouse NACC1 CRISPR Stable Knockout ID8 Cell Line - Clone T1-23

T6826 1x10^6 cells / 1.0 ml
EUR 3950

PTPN6 Stable Knocked Out THP-1 Cell Line

T6216 1x10^6 cells / 1.0 ml
EUR 3950

SIRT1 Wildtype Stable 293T Cell Line

T3175 1x10^6 cells / 1.0 ml
EUR 3950

Platinum-E Retroviral Packaging Cell Line, Ecotropic

RV-101 1 vial
EUR 770

Platinum-GP Retroviral Packaging Cell Line, Pantropic

RV-103 1 vial
EUR 770

Platinum-A Retroviral Packaging Cell Line, Amphotropic

RV-102 1 vial
EUR 770

Total Protein - Murine Embryonic Stem Cell Line D3

CBA-305 500 ?g
EUR 414
Description:
  • Isolated from mouse ES-D3 cell line
  • Presented as 500 µg at 1 mg/mL in NP-40 Solubilization Buffer

PGC-1α/ERRα Stable 293T Cell Line

T3060 1x10^6 cells / 1.0 ml
EUR 385

Mouse R-spondin1 Stable 293T Cell Line

T3156 1x10^6 cells / 1.0 ml
EUR 3950

BRCA1 CRISPR Stable Knockout Human Fibroblast Cell Line

T6245 1x10^6 cells / 1.0 ml
EUR 3950

PFN2 Stable Expressing 293T Cell Line - Polyclonal

T9606 1x10^6 cells / 1.0 ml
EUR 3950

PLN Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS41 1 Vial
EUR 2268

LRP1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS31 1 Vial
EUR 2268

AFF2 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS61 1 Vial
EUR 2268

ABCA7 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS21 1 Vial
EUR 2268

KCNK3 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS51 1 Vial
EUR 2268

LLGL1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS71 1 Vial
EUR 2268

TARGATT? Knock-in Mouse Cell Line Generation Kit (Master Cell Line)

AST-7001 1 Kit Ask for price
Description: 6 month

GZMA 3'UTR GFP Stable Cell Line

TU059495 1.0 ml
EUR 1672.8

Gzma 3'UTR GFP Stable Cell Line

TU255597 1.0 ml Ask for price

Gzma 3'UTR GFP Stable Cell Line

TU159260 1.0 ml Ask for price

Human CRISP1 knockout cell line

ABC-KH3569 1 vial Ask for price
Description: Human CRISP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISP2 knockout cell line

ABC-KH3570 1 vial Ask for price
Description: Human CRISP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISP3 knockout cell line

ABC-KH3571 1 vial Ask for price
Description: Human CRISP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

PTPRA CRISPR Knockout Immortalized Human Lung Fibroblast Cell Line

T6827 1x10^6 cells / 1.0 ml Ask for price

YBX1 Stable Knockout Human NK/T Cell Line #T3-16 P6

T9508 1x10^6 cells / 1.0 ml Ask for price

Human GZMB knockout cell line

ABC-KH6567 1 vial Ask for price
Description: Human GZMB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GZMH knockout cell line

ABC-KH6568 1 vial Ask for price
Description: Human GZMH knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GZMK knockout cell line

ABC-KH6569 1 vial Ask for price
Description: Human GZMK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GZMM knockout cell line

ABC-KH6570 1 vial Ask for price
Description: Human GZMM knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISPLD1 knockout cell line

ABC-KH3572 1 vial Ask for price
Description: Human CRISPLD1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISPLD2 knockout cell line

ABC-KH3573 1 vial Ask for price
Description: Human CRISPLD2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

TARGATT? Knock-in iPSC Generation (Master Cell Line)

AST-1100 1 vial of 1X10^6 cells Ask for price
Description: 6 month

Gzma 3'UTR Luciferase Stable Cell Line

TU205597 1.0 ml Ask for price

GZMA 3'UTR Luciferase Stable Cell Line

TU009495 1.0 ml
EUR 1672.8

Gzma 3'UTR Luciferase Stable Cell Line

TU109260 1.0 ml Ask for price

Human 293T Cell Lysate Lyophilized

IHU293TTLLY200UG each
EUR 89
Description: Human 293T Cell Lysate Lyophilized

Acan CRISPR Knockout RCS Cell Line (Rat)

T3000 1x10^6 cells / 1.0 ml Ask for price

Human CRISP1 knockdown cell line

ABC-KD3569 1 vial Ask for price
Description: Human CRISP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISP2 knockdown cell line

ABC-KD3570 1 vial Ask for price
Description: Human CRISP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISP3 knockdown cell line

ABC-KD3571 1 vial Ask for price
Description: Human CRISP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human 293T Whole Cell Lysate

LYSATE0032 200ug
EUR 180
Description: This cell lysate is prepared from human 293T using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Human GZMB knockdown cell line

ABC-KD6567 1 vial Ask for price
Description: Human GZMB knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human GZMH knockdown cell line

ABC-KD6568 1 vial Ask for price
Description: Human GZMH knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human GZMK knockdown cell line

ABC-KD6569 1 vial Ask for price
Description: Human GZMK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human GZMM knockdown cell line

ABC-KD6570 1 vial Ask for price
Description: Human GZMM knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISPLD1 knockdown cell line

ABC-KD3572 1 vial Ask for price
Description: Human CRISPLD1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISPLD2 knockdown cell line

ABC-KD3573 1 vial Ask for price
Description: Human CRISPLD2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

TARGATT? Knock-in CHO Generation Kit (Master Cell Line)

AST-1200 1 Kit Ask for price
Description: 12 month

VEGF Promoter Stable Expressing 293T Cell Line - Clone #2

T9622 1x10^6 cells / 1.0 ml
EUR 3950

AAVS1 Positive Control EGIP 293T Reporter Cell Line

CAS606A-1 1 Vial
EUR 726

TARGATT? Knock-in HEK293 Generation Kit (Master Cell Line)

AST-1300 1 Kit Ask for price
Description: 12 month

GFAT1 CRISPR Stable Knockout H1299 Cell Line

T6199 1x10^6 cells / 1.0 ml
EUR 3950

EDC4 CRISPR Stable Knockout HEK293T Cell Line

T6241 1x10^6 cells / 1.0 ml
EUR 3950

293T Cell Lysates

GWB-E5C7FC 0.2 mg Ask for price

DJ-1 CRISPR Stable Knockout HeLa Cell Line

T6181 1x10^6 cells / 1.0 ml
EUR 3950

PDPN CRISPR Stable Knockout COS-7 Cell Line

T6039 1x10^6 cells / 1.0 ml
EUR 3950

PD-L1 CRISPR Stable Knockout CT26 Cell Line

T6237 1x10^6 cells / 1.0 ml
EUR 3950

PD-L1 CRISPR Stable Knockout MC38 Cell Line

T6149 1x10^6 cells / 1.0 ml
EUR 3950

GZMA sgRNA CRISPR Lentivector set (Human)

K0923801 3 x 1.0 ug
EUR 406.8

LIMD1-/- CRISPR Stable Knockout HeLa Cell Line

T6357 1x10^6 cells / 1.0 ml
EUR 3950

SLC35A1 CRISPR Stable Knockout CHO-S Cell Line

T6040 1x10^6 cells / 1.0 ml
EUR 3950

CXCL1 & CXCL8 CRISPR Double Knockout L3.6pl Cell Line

T6047 1x10^6 cells / 1.0 ml Ask for price

AXL CRISPR Stable Knockout HT1080 (1-IV) Cell Line

T6232 1x10^6 cells / 1.0 ml
EUR 3950

AXL CRISPR Stable Knockout HT1080 (3-II) Cell Line

T6233 1x10^6 cells / 1.0 ml
EUR 3950

hCETP shRNA (Target C) Knock Down THP-1 Cell Line-Polyclone

T9789 1x10^6 cells / 1.0 ml Ask for price

Human CRIM1 knockout cell line

ABC-KH3563 1 vial Ask for price
Description: Human CRIM1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP1 knockout cell line

ABC-KH3564 1 vial Ask for price
Description: Human CRIP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP2 knockout cell line

ABC-KH3565 1 vial Ask for price
Description: Human CRIP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP3 knockout cell line

ABC-KH3566 1 vial Ask for price
Description: Human CRIP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIPT knockout cell line

ABC-KH3568 1 vial Ask for price
Description: Human CRIPT knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

GZMA sgRNA CRISPR Lentivector (Human) (Target 1)

K0923802 1.0 ug DNA
EUR 184.8

GZMA sgRNA CRISPR Lentivector (Human) (Target 2)

K0923803 1.0 ug DNA
EUR 184.8

GZMA sgRNA CRISPR Lentivector (Human) (Target 3)

K0923804 1.0 ug DNA
EUR 184.8

Human CRIPAK knockout cell line

ABC-KH3567 1 vial Ask for price
Description: Human CRIPAK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Cas9 (CRISPR Associated Protein 9) ELISA Kit

PRB-5079 96 assays
EUR 485

Human CRIM1 knockdown cell line

ABC-KD3563 1 vial Ask for price
Description: Human CRIM1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP1 knockdown cell line

ABC-KD3564 1 vial Ask for price
Description: Human CRIP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP2 knockdown cell line

ABC-KD3565 1 vial Ask for price
Description: Human CRIP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP3 knockdown cell line

ABC-KD3566 1 vial Ask for price
Description: Human CRIP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIPT knockdown cell line

ABC-KD3568 1 vial Ask for price
Description: Human CRIPT knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIPAK knockdown cell line

ABC-KD3567 1 vial Ask for price
Description: Human CRIPAK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human LIN37 knockout cell line

ABC-KH8476 1 vial Ask for price
Description: Human LIN37 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GC knockout cell line

ABC-KH5948 1 vial Ask for price
Description: Human GC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GK knockout cell line

ABC-KH6087 1 vial Ask for price
Description: Human GK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human HP knockout cell line

ABC-KH6972 1 vial Ask for price
Description: Human HP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human HR knockout cell line

ABC-KH6992 1 vial Ask for price
Description: Human HR knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human KL knockout cell line

ABC-KH7942 1 vial Ask for price
Description: Human KL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human KY knockout cell line

ABC-KH8250 1 vial Ask for price
Description: Human KY knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human MB knockout cell line

ABC-KH9065 1 vial Ask for price
Description: Human MB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F2 knockout cell line

ABC-KH5009 1 vial Ask for price
Description: Human F2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F3 knockout cell line

ABC-KH5014 1 vial Ask for price
Description: Human F3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F5 knockout cell line

ABC-KH5015 1 vial Ask for price
Description: Human F5 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F7 knockout cell line

ABC-KH5016 1 vial Ask for price
Description: Human F7 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F8 knockout cell line

ABC-KH5017 1 vial Ask for price
Description: Human F8 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F9 knockout cell line

ABC-KH5021 1 vial Ask for price
Description: Human F9 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human AR knockout cell line

ABC-KH0856 1 vial Ask for price
Description: Human AR knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human SI knockout cell line

ABC-KH13776 1 vial Ask for price
Description: Human SI knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human T knockout cell line

ABC-KH15011 1 vial Ask for price
Description: Human T knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human TF knockout cell line

ABC-KH15318 1 vial Ask for price
Description: Human TF knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human TG knockout cell line

ABC-KH15342 1 vial Ask for price
Description: Human TG knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human TH knockout cell line

ABC-KH15368 1 vial Ask for price
Description: Human TH knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human PC knockout cell line

ABC-KH11173 1 vial Ask for price
Description: Human PC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human XG knockout cell line

ABC-KH17067 1 vial Ask for price
Description: Human XG knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human XK knockout cell line

ABC-KH17074 1 vial Ask for price
Description: Human XK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CP knockout cell line

ABC-KH3480 1 vial Ask for price
Description: Human CP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CS knockout cell line

ABC-KH3611 1 vial Ask for price
Description: Human CS knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C2 knockout cell line

ABC-KH1951 1 vial Ask for price
Description: Human C2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C3 knockout cell line

ABC-KH2027 1 vial Ask for price
Description: Human C3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C5 knockout cell line

ABC-KH2074 1 vial Ask for price
Description: Human C5 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C6 knockout cell line

ABC-KH2100 1 vial Ask for price
Description: Human C6 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C7 knockout cell line

ABC-KH2130 1 vial Ask for price
Description: Human C7 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C9 knockout cell line

ABC-KH2174 1 vial Ask for price
Description: Human C9 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Cas13a (CRISPR Associated Protein 13a, C2c2) ELISA Kit

PRB-5091 96 assays
EUR 686.4

Human CEL knockout cell line

ABC-KH2905 1 vial Ask for price
Description: Human CEL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LINS knockout cell line

ABC-KH8486 1 vial Ask for price
Description: Human LINS knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN7A knockout cell line

ABC-KH8477 1 vial Ask for price
Description: Human LIN7A knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN7B knockout cell line

ABC-KH8478 1 vial Ask for price
Description: Human LIN7B knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN7C knockout cell line

ABC-KH8479 1 vial Ask for price
Description: Human LIN7C knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN28A knockout cell line

ABC-KH8474 1 vial Ask for price
Description: Human LIN28A knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN28B knockout cell line

ABC-KH8475 1 vial Ask for price
Description: Human LIN28B knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human NDN knockout cell line

ABC-KH9930 1 vial Ask for price
Description: Human NDN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human NDP knockout cell line

ABC-KH9934 1 vial Ask for price
Description: Human NDP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human NEB knockout cell line

ABC-KH9989 1 vial Ask for price
Description: Human NEB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FRK knockout cell line

ABC-KH5720 1 vial Ask for price
Description: Human FRK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FRY knockout cell line

ABC-KH5737 1 vial Ask for price
Description: Human FRY knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FST knockout cell line

ABC-KH5752 1 vial Ask for price
Description: Human FST knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FTL knockout cell line

ABC-KH5760 1 vial Ask for price
Description: Human FTL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FTO knockout cell line

ABC-KH5762 1 vial Ask for price
Description: Human FTO knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FUK knockout cell line

ABC-KH5768 1 vial Ask for price
Description: Human FUK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FUS knockout cell line

ABC-KH5773 1 vial Ask for price
Description: Human FUS knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FUZ knockout cell line

ABC-KH5784 1 vial Ask for price
Description: Human FUZ knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FYB knockout cell line

ABC-KH5795 1 vial Ask for price
Description: Human FYB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FYN knockout cell line

ABC-KH5797 1 vial Ask for price
Description: Human FYN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GAA knockout cell line

ABC-KH5817 1 vial Ask for price
Description: Human GAA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GAK knockout cell line

ABC-KH5864 1 vial Ask for price
Description: Human GAK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GAL knockout cell line

ABC-KH5865 1 vial Ask for price
Description: Human GAL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GAN knockout cell line

ABC-KH5901 1 vial Ask for price
Description: Human GAN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GBA knockout cell line

ABC-KH5934 1 vial Ask for price
Description: Human GBA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GCA knockout cell line

ABC-KH5949 1 vial Ask for price
Description: Human GCA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GCG knockout cell line

ABC-KH5955 1 vial Ask for price
Description: Human GCG knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GCK knockout cell line

ABC-KH5959 1 vial Ask for price
Description: Human GCK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Dodaj komentarz

Twój adres e-mail nie zostanie opublikowany. Wymagane pola są oznaczone *