Sierocy receptor jądrowy RORgammat
Sierocy receptor jądrowy RORgammat kieruje programem różnicowania prozapalnych komórek pomocniczych IL-17 + T.
IL-17-producing T lymphocytes have been lately proven to comprise a definite lineage of proinflammatory T helper cells, termed Th17 cells, which can be main contributors to autoimmune illness. We present right here that the orphan nuclear receptor RORgammat is the important thing transcription issue that orchestrates the differentiation of this effector cell lineage. RORgammat induces transcription of the genes encoding IL-17 and the associated cytokine IL-17F in naïve CD4(+) T helper cells and is required for his or her expression in response to IL-6 and TGF-beta, the cytokines identified to induce IL-17.
Th17 cells are constitutively current all through the intestinal lamina propria, categorical RORgammat, and are absent in mice poor for RORgammat or IL-6. Mice with RORgammat-deficient T cells have attenuated autoimmune illness and lack tissue-infiltrating Th17 cells. Collectively, these research counsel that RORgammat is a key regulator of immune homeostasis and spotlight its potential as a therapeutic goal in inflammatory ailments.
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Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika sprzyja przywilejowi immunologicznemu i pozwala przewidzieć skrócenie czasu przeżycia.
Regulatory T (T(reg)) cells mediate homeostatic peripheral tolerance by suppressing autoreactive T cells. Failure of host antitumor immunity could also be attributable to exaggerated suppression of tumor-associated antigen-reactive lymphocytes mediated by T(reg) cells; nevertheless, definitive proof that T(reg) cells have an immunopathological function in human most cancers is missing. Right here we present, in detailed research of CD4(+)CD25(+)FOXP3(+) T(reg) cells in 104 people affected with ovarian carcinoma, that human tumor T(reg) cells suppress tumor-specific T cell immunity and contribute to progress of human tumors in vivo.
We additionally present that tumor T(reg) cells are related to a excessive demise hazard and decreased survival. Human T(reg) cells preferentially transfer to and accumulate in tumors and ascites, however not often enter draining lymph nodes in later most cancers phases. Tumor cells and microenvironmental macrophages produce the chemokine CCL22, which mediates trafficking of T(reg) cells to the tumor. This particular recruitment of T(reg) cells represents a mechanism by which tumors might foster immune privilege. Thus, blocking T(reg) cell migration or perform might assist to defeat human most cancers.
Płynny mannequin mozaiki struktury błon komórkowych.
A fluid mosaic mannequin is offered for the gross group and construction of the proteins and lipids of organic membranes. The mannequin is according to the restrictions imposed by thermodynamics. On this mannequin, the proteins which can be integral to the membrane are a heterogeneous set of globular molecules, every organized in an amphipathic construction, that’s, with the ionic and extremely polar teams protruding from the membrane into the aqueous part, and the nonpolar teams largely buried within the hydrophobic inside of the membrane. These globular molecules are partially embedded in a matrix of phospholipid. The majority of the phospholipid is organized as a discontinuous, fluid bilayer, though a small fraction of the lipid might work together particularly with the membrane proteins.
The fluid mosaic construction is due to this fact formally analogous to a two-dimensional oriented resolution of integral proteins (or lipoproteins) within the viscous phospholipid bilayer solvent. Current experiments with all kinds of techniqes and several other totally different membrane methods are described, all of which abet according to, and add a lot element to, the fluid mosaic mannequin. It due to this fact appears acceptable to counsel potential mechanisms for varied membrane capabilities and membrane-mediated phenomena within the mild of the mannequin. As examples, experimentally testable mechanisms are prompt for cell floor adjustments in malignant transformation, and for cooperative results exhibited within the interactions of membranes with some particular ligands.
Notice added in proof: Since this text was written, we’ve obtained electron microscopic proof (69) that the concanavalin A binding websites on the membranes of SV40 virus-transformed mouse fibroblasts (3T3 cells) are extra clustered than the websites on the membranes of regular cells, as predicted by the speculation represented in Fig. 7B. T-here has additionally appeared a examine by Taylor et al. (70) displaying the exceptional results produced on lymphocytes by the addition of antibodies directed to their floor immunoglobulin molecules.
The antibodies induce a redistribution and pinocytosis of those floor immunoglobulins, in order that inside about 30 minutes at 37 levels C the floor immunoglobulins are utterly swept out of the membrane. These results don’t happen, nevertheless, if the bivalent antibodies are changed by their univalent Fab fragments or if the antibody experiments are carried out at zero levels C as an alternative of 37 levels C. These and associated outcomes strongly point out that the bivalent antibodies produce an aggregation of the floor immunoglobulin molecules within the airplane of the membrane, which may happen provided that the immunoglobulin molecules are free to diffuse within the membrane. This aggregation then seems to set off the pinocytosis of the membrane parts by some unknown mechanism. Such membrane transformations could also be of essential significance within the induction of an antibody response to an antigen, in addition to iv different processes of cell differentiation.
Przywracanie funkcji wyczerpanych limfocytów T CD8 podczas przewlekłej infekcji wirusowej.
Practical impairment of antigen-specific T cells is a defining attribute of many power infections, however the underlying mechanisms of T-cell dysfunction usually are not properly understood. To deal with this query, we analysed genes expressed in functionally impaired virus-specific CD8 T cells current in mice chronically contaminated with lymphocytic choriomeningitis virus (LCMV), and in contrast these with the gene profile of purposeful reminiscence CD8 T cells. Right here we report that PD-1 (programmed demise 1; often known as Pdcd1) was selectively upregulated by the exhausted T cells, and that in vivo administration of antibodies that blocked the interplay of this inhibitory receptor with its ligand, PD-L1 (often known as B7-H1), enhanced T-cell responses.
Notably, we discovered that even in persistently contaminated mice that had been missing CD4 T-cell assist, blockade of the PD-1/PD-L1 inhibitory pathway had a useful impact on the ‘helpless’ CD8 T cells, restoring their capacity to endure proliferation, secrete cytokines, kill contaminated cells and reduce viral load. Blockade of the CTLA-4 (cytotoxic T-lymphocyte-associated protein 4) inhibitory pathway had no impact on both T-cell perform or viral management. These research establish a particular mechanism of T-cell exhaustion and outline a probably efficient immunological technique for the remedy of power viral infections.
Ccl2 CRISPR Knock Out CT26 Cell Line |
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| T9611 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
CXCL8 CRISPR Knock Out L3.6pl Cell Line |
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| T6220 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
CXCL1 CRISPR Knock Out L3.6pl Cell Line |
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| T6221 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
NR2F6 CRISPR Knock Out Human Jurkat E6.1 Cell Line - Clone T3-10 |
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| T6822 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
TREM2 CRISPR Knock Out Human THP-1 Cell Line - Clone T1-9 |
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| T6810 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
PTPN6 CRISPR Knock Out Human THP-1 Cell Line - Clone T3-1 |
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| T6813 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
Aldh2 CRISPR Knock Out L929 Cell Line - Clone T3-20 |
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| T9692 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
PTPN11 CRISPR Knock Out NIH/3T3 Cell Line - Clone T4-9 |
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| T6803 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
PRSS21 CRISPR Knock Out Human OVCAR8 Cell Line - Clone T2 C8 |
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| T6811 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
METTL3 CRISPR Knock Out Caki-1 Cell Line - Clone T2-16 |
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| T9623 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Nacc1 CRISPR Knock Out ID8 Cell Line (Mouse) - Clone T1-23 |
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| T9627 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
osbpl2 CRISPR Knock Out NIH/3T3 Cell Line - T1 Polyclonal Pool |
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| T9682 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
GLT1 CRISPR Knock Out Rat AST Cell Line - Clone T2-1 |
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| T9678 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
Aifm1 CRISPR Knock Out Mouse L929 Cell Line - Clone T2-15-3 |
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| T9674 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
SEC61G CRISPR Knock Out HCC-LM3 Cell Line - Clone T2-17-5 |
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| T9746 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
MSLN CRISPR Knock Out Human OVCAR3-A1 Cell Line - Clone T2 C4 |
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| T6820 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
CARMIL1 CRISPR Knock Out Immortalized Human Gingival Fibroblast - hTERT Cell Line - T1-2 |
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| T6825 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
hPIM1 CRISPR Knock Out SACC-83 Cell Line-T3-9 |
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| T9787 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
Dcx CRISPR Knock Out C6 Cell Line (Rat) - Clone sg4-1 |
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| T9624 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Human GZMA knockout cell line |
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| ABC-KH6566 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Cell line gene knock-in and knock-out |
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| S301 | 101Bio | - | EUR 15000 |
Human GZMA knockdown cell line |
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| ABC-KD6566 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMA knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T1-19 |
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| T9511 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T3-3 |
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| T9529 | ABM | 1x10^6 cells/1.0ml | EUR 3950 |
SIRT1 Knockout Stable 293T Cell Line |
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| T3176 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
T47D/GFP Cell Line |
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| AKR-208 | Cell Biolabs | 1 vial | EUR 686.4 |
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Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
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Stable Mouse Myeloid-derived Suppressor-like LAL Knock Out (HD1B) Cell Line |
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| T3187 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
293T Cell Line |
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| LV010 | ABM | 1x10^6 | EUR 450 |
293T [HEK-293T] Cell Line |
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| CL-0005 | Elabscience Biotech | 1×10⁶ cells/vial | EUR 420 |
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Description: Homo sapiens, Human |
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Mouse NACC1 CRISPR Stable Knockout ID8 Cell Line - Clone T1-23 |
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| T6826 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
293T/17 Cell Line |
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| CL-0469 | Elabscience Biotech | 1×10⁶ cells/vial | EUR 500 |
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Description: Homo sapiens, Human |
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293T Cell Lysate (Human embryonic kidney cell line) |
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| LF-R0006 | Abfrontier | 200 ul | EUR 103.2 |
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Description: 293T (Human embryonic kidney cell line) Whole Cell Lysate |
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BRCA1 CRISPR Stable Knockout Human Fibroblast Cell Line |
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| T6245 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Blank Promoter Stable Expressing Human 293T Cell Line |
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| T9618 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
PTPRA CRISPR Knockout Immortalized Human Lung Fibroblast Cell Line |
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| T6827 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
293AD Cell Line |
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| AD-100 | Cell Biolabs | 1 vial | EUR 365 |
293AAV Cell Line |
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| AAV-100 | Cell Biolabs | 1 vial | EUR 405 |
293LTV Cell Line |
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| LTV-100 | Cell Biolabs | 1 vial | EUR 405 |
293RTV Cell Line |
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| RV-100 | Cell Biolabs | 1 vial | EUR 405 |
Cas9 Expressing 293T Cell Line |
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| T3251 | ABM | 1x10^6 cells / 1.0 ml | EUR 795 |
293/GFP Cell Line |
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| AKR-200 | Cell Biolabs | 1 vial | EUR 460 |
Human CRISP1 knockout cell line |
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| ABC-KH3569 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CRISP2 knockout cell line |
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| ABC-KH3570 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CRISP3 knockout cell line |
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| ABC-KH3571 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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A549/GFP Cell Line |
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| AKR-209 | Cell Biolabs | 1 vial | EUR 460 |
HeLa/GFP Cell Line |
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| AKR-213 | Cell Biolabs | 1 vial | EUR 460 |
293/Cas9 Cell Line |
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| AKR-5110 | Cell Biolabs | 1 vial | EUR 460 |
HeLa/Cas9 Cell Line |
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| AKR-5111 | Cell Biolabs | 1 vial | EUR 460 |
NIH3T3/GFP Cell Line |
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| AKR-214 | Cell Biolabs | 1 vial | EUR 460 |
Stable 293T-ATD cell line |
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| T6340 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
NIH3T3/Cas9 Cell Line |
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| AKR-5104 | Cell Biolabs | 1 vial | EUR 460 |
Acan CRISPR Knockout RCS Cell Line (Rat) |
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| T3000 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
PTPN6 Stable Knocked Out THP-1 Cell Line |
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| T6216 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Human CRISPLD1 knockout cell line |
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| ABC-KH3572 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISPLD1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CRISPLD2 knockout cell line |
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| ABC-KH3573 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISPLD2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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MCF-7/Luc Cell Line |
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| AKR-234 | Cell Biolabs | 1 vial | EUR 686.4 |
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Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line. |
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SKOV-3/Luc Cell Line |
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| AKR-232 | Cell Biolabs | 1 vial | EUR 686.4 |
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Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line. |
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OVCAR-5/RFP Cell Line |
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| AKR-254 | Cell Biolabs | 1 vial | EUR 686.4 |
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Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line. |
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Human CRISP1 knockdown cell line |
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| ABC-KD3569 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human CRISP2 knockdown cell line |
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| ABC-KD3570 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human CRISP3 knockdown cell line |
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| ABC-KD3571 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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SIRT1 Wildtype Stable 293T Cell Line |
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| T3175 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
TARGATT? Knock-in Mouse Cell Line Generation Kit (Master Cell Line) |
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| AST-7001 | Applied StemCell | 1 Kit | Ask for price |
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Description: 6 month |
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Human CRISPLD1 knockdown cell line |
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| ABC-KD3572 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISPLD1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human CRISPLD2 knockdown cell line |
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| ABC-KD3573 | AcceGen | 1 vial | Ask for price |
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Description: Human CRISPLD2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human GZMB knockout cell line |
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| ABC-KH6567 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GZMH knockout cell line |
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| ABC-KH6568 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMH knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GZMK knockout cell line |
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| ABC-KH6569 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GZMM knockout cell line |
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| ABC-KH6570 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMM knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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GFAT1 CRISPR Stable Knockout H1299 Cell Line |
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| T6199 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
EDC4 CRISPR Stable Knockout HEK293T Cell Line |
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| T6241 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
DJ-1 CRISPR Stable Knockout HeLa Cell Line |
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| T6181 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
PGC-1α/ERRα Stable 293T Cell Line |
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| T3060 | ABM | 1x10^6 cells / 1.0 ml | EUR 385 |
YBX1 Stable Knockout Human NK/T Cell Line #T3-16 P6 |
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| T9508 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
PDPN CRISPR Stable Knockout COS-7 Cell Line |
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| T6039 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
PD-L1 CRISPR Stable Knockout CT26 Cell Line |
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| T6237 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
PD-L1 CRISPR Stable Knockout MC38 Cell Line |
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| T6149 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
LIMD1-/- CRISPR Stable Knockout HeLa Cell Line |
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| T6357 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Mouse R-spondin1 Stable 293T Cell Line |
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| T3156 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
TARGATT? Knock-in iPSC Generation (Master Cell Line) |
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| AST-1100 | Applied StemCell | 1 vial of 1X10^6 cells | Ask for price |
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Description: 6 month |
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SLC35A1 CRISPR Stable Knockout CHO-S Cell Line |
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| T6040 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
CXCL1 & CXCL8 CRISPR Double Knockout L3.6pl Cell Line |
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| T6047 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
Human GZMB knockdown cell line |
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| ABC-KD6567 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMB knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human GZMH knockdown cell line |
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| ABC-KD6568 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMH knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human GZMK knockdown cell line |
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| ABC-KD6569 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human GZMM knockdown cell line |
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| ABC-KD6570 | AcceGen | 1 vial | Ask for price |
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Description: Human GZMM knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Platinum-E Retroviral Packaging Cell Line, Ecotropic |
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| RV-101 | Cell Biolabs | 1 vial | EUR 770 |
Platinum-GP Retroviral Packaging Cell Line, Pantropic |
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| RV-103 | Cell Biolabs | 1 vial | EUR 770 |
Platinum-A Retroviral Packaging Cell Line, Amphotropic |
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| RV-102 | Cell Biolabs | 1 vial | EUR 770 |
PFN2 Stable Expressing 293T Cell Line - Polyclonal |
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| T9606 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Total Protein - Murine Embryonic Stem Cell Line D3 |
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| CBA-305 | Cell Biolabs | 500 ?g | EUR 414 |
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Description:
|
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PLN Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) |
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| iPS41 | ALSTEM | 1 Vial | EUR 2268 |
AXL CRISPR Stable Knockout HT1080 (1-IV) Cell Line |
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| T6232 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
AXL CRISPR Stable Knockout HT1080 (3-II) Cell Line |
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| T6233 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
LRP1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) |
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| iPS31 | ALSTEM | 1 Vial | EUR 2268 |
AFF2 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) |
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| iPS61 | ALSTEM | 1 Vial | EUR 2268 |
ABCA7 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) |
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| iPS21 | ALSTEM | 1 Vial | EUR 2268 |
KCNK3 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) |
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| iPS51 | ALSTEM | 1 Vial | EUR 2268 |
LLGL1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) |
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| iPS71 | ALSTEM | 1 Vial | EUR 2268 |
TARGATT? Knock-in CHO Generation Kit (Master Cell Line) |
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| AST-1200 | Applied StemCell | 1 Kit | Ask for price |
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Description: 12 month |
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TARGATT? Knock-in HEK293 Generation Kit (Master Cell Line) |
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| AST-1300 | Applied StemCell | 1 Kit | Ask for price |
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Description: 12 month |
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GZMA 3'UTR GFP Stable Cell Line |
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| TU059495 | ABM | 1.0 ml | EUR 1672.8 |
Gzma 3'UTR GFP Stable Cell Line |
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| TU255597 | ABM | 1.0 ml | Ask for price |
Gzma 3'UTR GFP Stable Cell Line |
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| TU159260 | ABM | 1.0 ml | Ask for price |
Human CRIM1 knockout cell line |
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| ABC-KH3563 | AcceGen | 1 vial | Ask for price |
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Description: Human CRIM1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CRIP1 knockout cell line |
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| ABC-KH3564 | AcceGen | 1 vial | Ask for price |
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Description: Human CRIP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CRIP2 knockout cell line |
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| ABC-KH3565 | AcceGen | 1 vial | Ask for price |
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Description: Human CRIP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CRIP3 knockout cell line |
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| ABC-KH3566 | AcceGen | 1 vial | Ask for price |
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Description: Human CRIP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CRIPT knockout cell line |
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| ABC-KH3568 | AcceGen | 1 vial | Ask for price |
|
Description: Human CRIPT knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CRIPAK knockout cell line |
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| ABC-KH3567 | AcceGen | 1 vial | Ask for price |
|
Description: Human CRIPAK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Gzma 3'UTR Luciferase Stable Cell Line |
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| TU205597 | ABM | 1.0 ml | Ask for price |
GZMA 3'UTR Luciferase Stable Cell Line |
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| TU009495 | ABM | 1.0 ml | EUR 1672.8 |
Gzma 3'UTR Luciferase Stable Cell Line |
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| TU109260 | ABM | 1.0 ml | Ask for price |
Human 293T Cell Lysate Lyophilized |
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| IHU293TTLLY200UG | Innovative research | each | EUR 89 |
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Description: Human 293T Cell Lysate Lyophilized |
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Human 293T Cell Lysate Lyophilized |
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| MBS136608-02mg | MyBiosource | 0.2mg | EUR 205 |
Human 293T Cell Lysate Lyophilized |
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| MBS136608-5x02mg | MyBiosource | 5x0.2mg | EUR 745 |
AAVS1 Positive Control EGIP 293T Reporter Cell Line |
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| CAS606A-1 | SBI | 1 Vial | EUR 726 |
GZMA sgRNA CRISPR Lentivector set (Human) |
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| K0923801 | ABM | 3 x 1.0 ug | EUR 406.8 |
VEGF Promoter Stable Expressing 293T Cell Line - Clone #2 |
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| T9622 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Human 293T Whole Cell Lysate |
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| LYSATE0032 | BosterBio | 200ug | EUR 180 |
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Description: This cell lysate is prepared from human 293T using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C. |
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Human CRIM1 knockdown cell line |
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| ABC-KD3563 | AcceGen | 1 vial | Ask for price |
|
Description: Human CRIM1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human CRIP1 knockdown cell line |
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| ABC-KD3564 | AcceGen | 1 vial | Ask for price |
|
Description: Human CRIP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human CRIP2 knockdown cell line |
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| ABC-KD3565 | AcceGen | 1 vial | Ask for price |
|
Description: Human CRIP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human CRIP3 knockdown cell line |
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| ABC-KD3566 | AcceGen | 1 vial | Ask for price |
|
Description: Human CRIP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human CRIPT knockdown cell line |
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| ABC-KD3568 | AcceGen | 1 vial | Ask for price |
|
Description: Human CRIPT knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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hCETP shRNA (Target C) Knock Down THP-1 Cell Line-Polyclone |
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| T9789 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
Human CRIPAK knockdown cell line |
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| ABC-KD3567 | AcceGen | 1 vial | Ask for price |
|
Description: Human CRIPAK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human LIN37 knockout cell line |
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| ABC-KH8476 | AcceGen | 1 vial | Ask for price |
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Description: Human LIN37 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GC knockout cell line |
|||
| ABC-KH5948 | AcceGen | 1 vial | Ask for price |
|
Description: Human GC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GK knockout cell line |
|||
| ABC-KH6087 | AcceGen | 1 vial | Ask for price |
|
Description: Human GK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human HP knockout cell line |
|||
| ABC-KH6972 | AcceGen | 1 vial | Ask for price |
|
Description: Human HP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human HR knockout cell line |
|||
| ABC-KH6992 | AcceGen | 1 vial | Ask for price |
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Description: Human HR knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human KL knockout cell line |
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| ABC-KH7942 | AcceGen | 1 vial | Ask for price |
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Description: Human KL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human KY knockout cell line |
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| ABC-KH8250 | AcceGen | 1 vial | Ask for price |
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Description: Human KY knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human MB knockout cell line |
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| ABC-KH9065 | AcceGen | 1 vial | Ask for price |
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Description: Human MB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human F2 knockout cell line |
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| ABC-KH5009 | AcceGen | 1 vial | Ask for price |
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Description: Human F2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human F3 knockout cell line |
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| ABC-KH5014 | AcceGen | 1 vial | Ask for price |
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Description: Human F3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human F5 knockout cell line |
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| ABC-KH5015 | AcceGen | 1 vial | Ask for price |
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Description: Human F5 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human F7 knockout cell line |
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| ABC-KH5016 | AcceGen | 1 vial | Ask for price |
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Description: Human F7 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human F8 knockout cell line |
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| ABC-KH5017 | AcceGen | 1 vial | Ask for price |
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Description: Human F8 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human F9 knockout cell line |
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| ABC-KH5021 | AcceGen | 1 vial | Ask for price |
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Description: Human F9 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human AR knockout cell line |
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| ABC-KH0856 | AcceGen | 1 vial | Ask for price |
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Description: Human AR knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human SI knockout cell line |
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| ABC-KH13776 | AcceGen | 1 vial | Ask for price |
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Description: Human SI knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human T knockout cell line |
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| ABC-KH15011 | AcceGen | 1 vial | Ask for price |
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Description: Human T knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human TF knockout cell line |
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| ABC-KH15318 | AcceGen | 1 vial | Ask for price |
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Description: Human TF knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human TG knockout cell line |
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| ABC-KH15342 | AcceGen | 1 vial | Ask for price |
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Description: Human TG knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human TH knockout cell line |
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| ABC-KH15368 | AcceGen | 1 vial | Ask for price |
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Description: Human TH knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human PC knockout cell line |
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| ABC-KH11173 | AcceGen | 1 vial | Ask for price |
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Description: Human PC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human XG knockout cell line |
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| ABC-KH17067 | AcceGen | 1 vial | Ask for price |
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Description: Human XG knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human XK knockout cell line |
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| ABC-KH17074 | AcceGen | 1 vial | Ask for price |
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Description: Human XK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CP knockout cell line |
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| ABC-KH3480 | AcceGen | 1 vial | Ask for price |
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Description: Human CP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CS knockout cell line |
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| ABC-KH3611 | AcceGen | 1 vial | Ask for price |
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Description: Human CS knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human C2 knockout cell line |
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| ABC-KH1951 | AcceGen | 1 vial | Ask for price |
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Description: Human C2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human C3 knockout cell line |
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| ABC-KH2027 | AcceGen | 1 vial | Ask for price |
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Description: Human C3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human C5 knockout cell line |
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| ABC-KH2074 | AcceGen | 1 vial | Ask for price |
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Description: Human C5 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human C6 knockout cell line |
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| ABC-KH2100 | AcceGen | 1 vial | Ask for price |
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Description: Human C6 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human C7 knockout cell line |
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| ABC-KH2130 | AcceGen | 1 vial | Ask for price |
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Description: Human C7 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human C9 knockout cell line |
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| ABC-KH2174 | AcceGen | 1 vial | Ask for price |
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Description: Human C9 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human CEL knockout cell line |
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| ABC-KH2905 | AcceGen | 1 vial | Ask for price |
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Description: Human CEL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human LIN7A knockout cell line |
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| ABC-KH8477 | AcceGen | 1 vial | Ask for price |
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Description: Human LIN7A knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human LIN7B knockout cell line |
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| ABC-KH8478 | AcceGen | 1 vial | Ask for price |
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Description: Human LIN7B knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human LIN7C knockout cell line |
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| ABC-KH8479 | AcceGen | 1 vial | Ask for price |
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Description: Human LIN7C knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human LINS knockout cell line |
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| ABC-KH8486 | AcceGen | 1 vial | Ask for price |
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Description: Human LINS knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human LIN28A knockout cell line |
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| ABC-KH8474 | AcceGen | 1 vial | Ask for price |
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Description: Human LIN28A knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human LIN28B knockout cell line |
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| ABC-KH8475 | AcceGen | 1 vial | Ask for price |
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Description: Human LIN28B knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human NDN knockout cell line |
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| ABC-KH9930 | AcceGen | 1 vial | Ask for price |
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Description: Human NDN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human NDP knockout cell line |
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| ABC-KH9934 | AcceGen | 1 vial | Ask for price |
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Description: Human NDP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human NEB knockout cell line |
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| ABC-KH9989 | AcceGen | 1 vial | Ask for price |
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Description: Human NEB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FRK knockout cell line |
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| ABC-KH5720 | AcceGen | 1 vial | Ask for price |
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Description: Human FRK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FRY knockout cell line |
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| ABC-KH5737 | AcceGen | 1 vial | Ask for price |
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Description: Human FRY knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FST knockout cell line |
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| ABC-KH5752 | AcceGen | 1 vial | Ask for price |
|
Description: Human FST knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FTL knockout cell line |
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| ABC-KH5760 | AcceGen | 1 vial | Ask for price |
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Description: Human FTL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FTO knockout cell line |
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| ABC-KH5762 | AcceGen | 1 vial | Ask for price |
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Description: Human FTO knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FUK knockout cell line |
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| ABC-KH5768 | AcceGen | 1 vial | Ask for price |
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Description: Human FUK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FUS knockout cell line |
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| ABC-KH5773 | AcceGen | 1 vial | Ask for price |
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Description: Human FUS knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FUZ knockout cell line |
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| ABC-KH5784 | AcceGen | 1 vial | Ask for price |
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Description: Human FUZ knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FYB knockout cell line |
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| ABC-KH5795 | AcceGen | 1 vial | Ask for price |
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Description: Human FYB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human FYN knockout cell line |
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| ABC-KH5797 | AcceGen | 1 vial | Ask for price |
|
Description: Human FYN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GAA knockout cell line |
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| ABC-KH5817 | AcceGen | 1 vial | Ask for price |
|
Description: Human GAA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GAK knockout cell line |
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| ABC-KH5864 | AcceGen | 1 vial | Ask for price |
|
Description: Human GAK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GAL knockout cell line |
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| ABC-KH5865 | AcceGen | 1 vial | Ask for price |
|
Description: Human GAL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GAN knockout cell line |
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| ABC-KH5901 | AcceGen | 1 vial | Ask for price |
|
Description: Human GAN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GBA knockout cell line |
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| ABC-KH5934 | AcceGen | 1 vial | Ask for price |
|
Description: Human GBA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GCA knockout cell line |
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| ABC-KH5949 | AcceGen | 1 vial | Ask for price |
|
Description: Human GCA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GCG knockout cell line |
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| ABC-KH5955 | AcceGen | 1 vial | Ask for price |
|
Description: Human GCG knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GCK knockout cell line |
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| ABC-KH5959 | AcceGen | 1 vial | Ask for price |
|
Description: Human GCK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GDA knockout cell line |
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| ABC-KH5974 | AcceGen | 1 vial | Ask for price |
|
Description: Human GDA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GEM knockout cell line |
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| ABC-KH5999 | AcceGen | 1 vial | Ask for price |
|
Description: Human GEM knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GFY knockout cell line |
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| ABC-KH6017 | AcceGen | 1 vial | Ask for price |
|
Description: Human GFY knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human GGH knockout cell line |
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| ABC-KH6024 | AcceGen | 1 vial | Ask for price |
|
Description: Human GGH knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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